Search results for " regulation"

showing 10 items of 3187 documents

The Greenland shark Somniosus microcephalus—Hemoglobins and ligand-binding properties

2017

A large amount of data is currently available on the adaptive mechanisms of polar bony fish hemoglobins, but structural information on those of cartilaginous species is scarce. This study presents the first characterisation of the hemoglobin system of one of the longest-living vertebrate species (392 +/- 120 years), the Arctic shark Somniosus microcephalus. Three major hemoglobins are found in its red blood cells and are made of two copies of the same a globin combined with two copies of three very similar beta subunits. The three hemoglobins show very similar oxygenation and carbonylation properties, which are unaffected by urea, a very important compound in marine elasmobranch physiology.…

---0301 basic medicinegenetic structuresProtein ConformationGreenlandlcsh:MedicineRESONANCE RAMAN-SPECTRAHETERODONTUS-PORTUSJACKSONISpectrum Analysis RamanBiochemistrychemistry.chemical_compoundHemoglobinsProtein structureAMINO-ACID SEQUENCEAnimal CellsSequence Analysis ProteinRed Blood CellsUreaNOTOTHENIOID FISHESPost-Translational Modificationlcsh:ScienceHemeChondrichthyesMultidisciplinarybiologyChemistryOrganic CompoundsChemical ReactionsVertebrateEukaryotaMOLECULAR ADAPTATIONSMicrocephalusGlobinsChemistryBiochemistryOptical EquipmentVertebratesPhysical SciencesEngineering and TechnologyCellular TypesResearch ArticleEnvironmental MonitoringProtein BindingQUATERNARY STRUCTURESAllosteric regulationEquipmentSTRETCHING FREQUENCIESHeme03 medical and health sciencesOXYGEN-BINDINGbiology.animalAnimals14. Life underwaterGlobinHemoglobinPhotolysisBlood Cells030102 biochemistry & molecular biologyLaserslcsh:ROrganic ChemistryOrganismsChemical CompoundsBiology and Life SciencesProteinsxxxCell Biologybiology.organism_classificationCARTILAGINOUS FISHOxygen030104 developmental biologySomniosusFishSharkslcsh:QHemoglobinProtein MultimerizationELASMOBRANCH HEMOGLOBINElasmobranchiiPLoS ONE
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Progress on bringing together raptor collections in Europe for contaminant research and monitoring in relation to chemicals regulation.

2019

Paola Movalli et al.

010504 meteorology & atmospheric sciences[SDV]Life Sciences [q-bio]Health Toxicology and MutagenesisSettore BIO/05 - Zoologia010501 environmental sciencesnatural history museum01 natural sciencesEnvironmental monitoringcollectionComputingMilieux_MISCELLANEOUSchemicals regulationenvironmental specimen bankEcologyPublished ErratumEnvironmental resource managementEnvironmental exposureGeneral MedicinePollutionEuropeChemistryGeographySpecimen collectionraptor[SDV.TOX]Life Sciences [q-bio]/Toxicology1181 Ecology evolutionary biologyEnvironmental PollutantscontaminantEnvironmental MonitoringResource (biology)Relation (database)MEDLINEchemicals managementChemical managementEnvironmental ChemistryEcotoxicologyAnimalscollectionsBiologyEnvironmental planning0105 earth and related environmental sciencesRaptorsbusiness.industryapex predator[SDE.ES]Environmental Sciences/Environmental and SocietymonitoringbiomonitoringSpecimen HandlingREACH[SDE.BE]Environmental Sciences/Biodiversity and EcologyEnvironmental specimenbusinessEnvironmental science and pollution research international
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PGDH family genes differentially affect Arabidopsis tolerance to salt stress

2019

The first step in the Phosphorylated Pathway of serine (Ser) Biosynthesis (PPSB) is catalyzed by the enzyme Phosphoglycerate Dehydrogenase (PGDH), coded in Arabidopsis thaliana by three genes. Gene expression analysis indicated that PGDH1 and PGDH2 were induced, while PGDH3 was repressed, by salt-stress. Accordingly, PGDH3 overexpressing plants (Oex PGDH3) were more sensitive to salinity than wild type plants (WT), while plants overexpressing PGDH1 (Oex PGDH1) performed better than WT under salinity conditions. Oex PGDH1 lines displayed lower levels of the salt-stress markers proline and raffinose in roots than WT under salt-stress conditions. Besides, the ratio of oxidized glutathione (GSS…

0106 biological sciences0301 basic medicineArabidopsisPlant SciencePlant Roots01 natural sciencesSerine03 medical and health scienceschemistry.chemical_compoundBiosynthesisGene Expression Regulation PlantArabidopsisGene expressionGeneticsArabidopsis thalianaPhosphoglycerate dehydrogenaseProlinePhosphoglycerate DehydrogenasebiologyArabidopsis ProteinsWild typeSalt ToleranceGeneral Medicinebiology.organism_classification030104 developmental biologychemistryBiochemistryMultigene FamilyAgronomy and Crop Science010606 plant biology & botanyPlant Science
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Survival and gene expression under different temperature and humidity regimes in ants

2017

Short term variation in environmental conditions requires individuals to adapt via changes in behavior and/or physiology. In particular variation in temperature and humidity are common, and the physiological adaptation to changes in temperature and humidity often involves alterations in gene expression, in particular that of heat-shock proteins. However, not only traits involved in the resistance to environmental stresses, but also other traits, such as immune defenses, may be influenced indirectly by changes in temperature and humidity. Here we investigated the response of the ant F. exsecta to two temperature regimes (20 degrees C & 25 degrees C), and two humidity regimes (50% & 75%), for…

0106 biological sciences0301 basic medicineAtmospheric ScienceympäristöAcclimatizationGene Expressionlcsh:MedicinemuutosALFALFA LEAFCUTTING BEEBiochemistryImmune Receptors01 natural sciencesEndocrinologyACCLIMATIONmuurahaisetGene expressionMedicine and Health SciencesIMMUNE-RESPONSEInsulinTRANSCRIPTIONgeeniekspressiolcsh:SciencePOPULATIONHeat-Shock ProteinsProtein MetabolismsopeutuminenPrincipal Component Analysiseducation.field_of_studyImmune System ProteinsMultidisciplinaryBehavior AnimalEcologyolosuhteetTemperaturefood and beveragesANThumanitiesInsectsimmuunijärjestelmä1181 Ecology evolutionary biologyPhysical SciencesMEGACHILE-ROTUNDATAlämpötilaympäristönmuutoksetResearch ArticleNutrient and Storage ProteinsSignal TransductionArthropodaImmunologyPopulationZoologyBiology010603 evolutionary biologyAcclimatization03 medical and health sciencesMeteorologyTwo temperatureStress PhysiologicalGeneticsAnimalseducationGeneProportional Hazards ModelsDiabetic EndocrinologyAntsBEAUVERIA-BASSIANAGene Expression Profilinglcsh:ROrganismshumidityBiology and Life SciencesProteinsHumiditytemperatureHumidityEigenvaluesCell BiologyDESICCATIONInvertebratesHymenopteraHormonesMetabolismAlgebra030104 developmental biologyGene Expression RegulationLinear AlgebraDROSOPHILA-MELANOGASTERkosteusEarth Sciencesgene expressionta1181lcsh:QFormica exsectaDesiccationRESISTANCEMathematics
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Interaction Between ABA Signaling and Copper Homeostasis inArabidopsis thaliana

2016

ABA is involved in plant responses to non-optimal environmental conditions, including nutrient availability. Since copper (Cu) is a very important micronutrient, unraveling how ABA affects Cu uptake and distribution is relevant to ensure adequate Cu nutrition in plants subjected to stress conditions. Inversely, knowledge about how the plant nutritional status can interfere with ABA biosynthesis and signaling mechanisms is necessary to optimize stress tolerance in horticultural crops. Here the reciprocal influence between ABA and Cu content was addressed by using knockout mutants and overexpressing transgenic plants of high affinity plasma membrane Cu transporters (pmCOPT) with altered Cu up…

0106 biological sciences0301 basic medicineBiologiaTranscription GeneticPhysiologyMutantArabidopsisPlant ScienceGenetically modified cropsSodium ChlorideGenes PlantPlant Roots01 natural sciencesGene Knockout Techniques03 medical and health scienceschemistry.chemical_compoundGene Expression Regulation PlantStress PhysiologicalArabidopsisHomeostasisArabidopsis thalianaPlantes Cèl·lules i teixitsAbscisic acidTranscription factorbiologyArabidopsis ProteinsMembrane transport proteinorganic chemicalsfungiMembrane Transport Proteinsfood and beveragesCell BiologyGeneral Medicinebiology.organism_classificationCell biologyOxidative StressPhenotype030104 developmental biologychemistryMutationbiology.proteinSignal transductionCopperAbscisic AcidSignal Transduction010606 plant biology & botanyPlant and Cell Physiology
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Essentiality Is a Strong Determinant of Protein Rates of Evolution during Mutation Accumulation Experiments in Escherichia coli

2016

[EN] The Neutral Theory of Molecular Evolution is considered the most powerful theory to understand the evolutionary behavior of proteins. One of the main predictions of this theory is that essential proteins should evolve slower than dispensable ones owing to increased selective constraints. Comparison of genomes of different species, however, has revealed only small differences between the rates of evolution ofessential and nonessential proteins. In some analyses, these differences vanish once confounding factors are controlled for, whereas in other cases essentiality seems to have an independent, albeit small, effect. It has been argued that comparing relatively distant genomes may entai…

0106 biological sciences0301 basic medicineBiologymedicine.disease_cause010603 evolutionary biology01 natural sciencesGenomeProtein evolutionEvolution Molecular03 medical and health sciencesGeneticsmedicineEscherichia colidN/dSProtein lengthEscherichia coliGeneEcology Evolution Behavior and Systematics2. Zero hungerGeneticsExperimental evolutionGenes EssentialModels GeneticEscherichia coli ProteinsGene Expression Regulation BacterialRates of evolutionMutation AccumulationNeutral theoryEssentiality030104 developmental biologyExperimental evolutionMutationNeutral theory of molecular evolutionGenome BacterialResearch Article
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Two maize Kip-related proteins differentially interact with, inhibit and are phosphorylated by cyclin D–cyclin-dependent kinase complexes

2017

Highlight Maize Kip-related proteins can be differentially phosphorylated by different cyclin D–cyclin-dependent kinase complexes and this influences their performance as cyclin-dependent kinase inhibitors.

0106 biological sciences0301 basic medicineCDKsPhysiologyCyclin DPlant Developmental BiologyPlant ScienceZea mays01 natural scienceslaw.inventionCyclins D03 medical and health sciencesGene Expression Regulation PlantCyclin-dependent kinaselawCyclin DPhosphorylationKinase activityKinase inhibitionCyclin-Dependent Kinase Inhibitor ProteinsPlant ProteinsbiologyKinaseKRP phosphorylationfood and beveragesICK/KRPsCyclin-Dependent Kinases030104 developmental biologyZea mays.Biochemistrybiology.proteinCyclin-dependent kinase complexRecombinant DNAPhosphorylationResearch Paper010606 plant biology & botanyCyclin-dependent kinase inhibitor proteinJournal of Experimental Botany
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A Complex Gene Network Mediated by Ethylene Signal Transduction TFs Defines the Flower Induction and Differentiation in Olea europaea L.

2021

The olive tree (Olea europaea L.) is a typical Mediterranean crop, important for olive and oil production. The high tendency to bear fruits in an uneven manner, defined as irregular or alternate bearing, results in a significant economic impact for the high losses in olives and oil production. Buds from heavy loaded (‘ON’) and unloaded (‘OFF’) branches of a unique olive tree were collected in July and the next March to compare the transcriptomic profiles and get deep insight into the molecular mechanisms regulating floral induction and differentiation. A wide set of DEGs related to ethylene TFs and to hormonal, sugar, and phenylpropanoid pathways was identified in buds collected from ‘OFF’ …

0106 biological sciences0301 basic medicineCandidate genelcsh:QH426-470Flower differentiationFlowersBiology01 natural sciencesArticleTranscriptome03 medical and health sciencesalternate bearingGene Expression Regulation PlantFlower inductionOleaBotanyGeneticsGene Regulatory NetworksOlea europaeaGeneGenetics (clinical)Plant ProteinsfloweringPhenylpropanoidfood and beveragesCell Differentiationtranscriptome profilingEthylenesbiology.organism_classificationOlive treesPlant Breedinglcsh:Genetics030104 developmental biologylateral budOleaNGS<i>Olea europaea</i>Transcriptome010606 plant biology & botanyTranscription FactorsGenes
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Daily rhythmicity of high affinity copper transport

2016

A differential demand for copper (Cu) of essential cupro-proteins that act within the mitochondrial and chloroplastal electronic transport chains occurs along the daily light/dark cycles. This requires a fine-tuned spatiotemporal regulation of Cu delivery, becoming especially relevant under non-optimal growth conditions. When scarce, Cu is imported through plasma membrane-bound high affinity Cu transporters (COPTs) whose coding genes are transcriptionally induced by the SPL7 transcription factor. Temporal homeostatic mechanisms are evidenced by the presence of multiple light- and clock-responsive regulatory cis elements in the promoters of both SPL7 and its COPT targets. A model is presente…

0106 biological sciences0301 basic medicineCircadian clockArabidopsisComputingMilieux_LEGALASPECTSOFCOMPUTINGPlant Science01 natural sciencesElectron Transport03 medical and health sciencesGene Expression Regulation PlantArabidopsisBotanyRNA MessengerSLC31 ProteinsPromoter Regions GeneticCation Transport ProteinsTranscription factorbiologyArabidopsis ProteinsGiganteaTransporterPromoterbiology.organism_classificationElectron transport chainArticle AddendumCircadian RhythmTransport proteinDNA-Binding Proteins030104 developmental biologyBiophysicsCopperMetabolic Networks and PathwaysTranscription Factors010606 plant biology & botanyPlant Signaling &amp; Behavior
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Gibberellin reactivates and maintains ovary-wall cell division causing fruit set in parthenocarpic Citrus species

2016

[EN] Citrus is a wide genus in which most of the cultivated species and cultivars are natural parthenocarpic mutants or hybrids (i.e. orange, mandarin, tangerine, grapefruit). The autonomous increase in GA(1) ovary concentration during anthesis was suggested as being the stimulus responsible for parthenocarpy in Citrus regardless of the species. To determine the exact GA-role in parthenocarpic fruit set, the following hypothesis was tested: GA triggers and maintains cell division in ovary walls causing fruit set. Obligate and facultative parthenocarpic Citrus species were used as a model system because obligate parthenocarpic Citrus sp (i.e. Citrus unshiu) have higher GA levels and better n…

0106 biological sciences0301 basic medicineCitrusCell divisionFruit setCitruFlowersPlant ScienceOrange (colour)BiologyParthenocarpy01 natural sciencesPaclobutrazol03 medical and health scienceschemistry.chemical_compoundPlant Growth RegulatorsGeneticAnthesisCell WallGene Expression Regulation PlantBotanyPRODUCCION VEGETALGeneticsGibberellinPhylogenyFruit treePlant Growth Regulatorfood and beveragesSequence Analysis DNAGeneral Medicinebiology.organism_classificationGibberellinsUp-RegulationCitrus unshiu030104 developmental biologychemistryFlowerFruitMicroscopy Electron ScanningParthenocarpyGibberellinAgronomy and Crop ScienceCell DivisionFruit tree010606 plant biology & botanyPlant Science
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